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Semax Research Peptide

Cognitive Research · Skin & Anti-Aging Research

Semax is a synthetic heptapeptide derived from ACTH (4–10), known for supporting BDNF expression and influencing the TrkB signaling pathway. It has been widely studied for its potential role in cognitive support, neuroprotection, and advanced peptide research applications.

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Semax Research Peptide

Cognitive Research · Skin & Anti-Aging Research

Select Dosage

Bundle & Save

1 bottle

Buy 2, Get 1 Free

$35.99

View certificate of analysis

Add BAC Water (needed for reconstitution)

Bacteriostatic water Research Peptide

$24.99

Select Dosage

🚚 Get 2 day shipping when you spend $250 or More

🚚 Free shipping over $200

🔄 60-day money back

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Certificate of Analysis and Peptide Purity Verification

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Third Party Tested by Freedom Diagnostics

Semax - 10mg Vial

Lot #2026-03-002-D

PASS

Verified Purity

Labeled 10mg

Actual 12.40 mg

Tested 08/09/2026

Method HPLC with UV Detection coupled with Mass Spectrometry (LC-MS)

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Compound Information

Technical specifications

🔬 MOLECULAR PROFILE

Semax Molecular Overview

Synthetic heptapeptide research peptide derived from the ACTH (4-10) sequence, utilized for studying BDNF expression and TrkB signaling dynamics.

Heptapeptide ACTH Analog

Type Synthetic heptapeptide

CAS Number 80714-61-0

Molecular Formula C37H51N9O10S

Molecular Weight 813.9 g/mol

Amino Acids 7 residues

Sequence Met-Glu-His-Phe-Pro-Gly-Pro

↗ PubChem Database

🧊 RESEARCH HANDLING

Handling and Context

Proper handling and storage are essential to maintain receptor interaction activity during experimental observations.

Light sensitive Temperature sensitive

❄️

Lyophilized (powder)

-20°C ・ protect from light

💉

Reconstituted Solution

2-8°C ・ use within 4 weeks

📋 EXPERIMENTAL CONTEXT

Observation Summary

Literature surrounding this receptor pathway research peptide focuses on its interaction with neurotrophic factors and genetic signaling.

Origin Russian Academy of Sciences

Research Focus Neurotrophic Pathway Studies

Primary Target BDNF & TrkB Expression

Observed Activity Receptor Interaction Dynamics

Experimental Use Laboratory Model Evaluation

Related Peptide Selank (tuftsin analog)

↗ Scientific Literature

Verified Reviews

What Researchers Say

4.8

Sample rating

Marcus T. ✓

Verified Buyer

Outstanding quality and fast, discreet shipping. Everything arrived exactly as described and the results in my research have been consistent. Will be ordering again.

Elena R. ✓

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Third-party testing gives me real peace of mind. Packaging was professional and the product purity is excellent. GMR has become my go-to supplier.

David K. ✓

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Great product and great value with the bundle offer. Delivery took a couple of days longer than expected, but the quality more than made up for it.

Sophia L.

Verified Buyer

Customer support was responsive and helpful when I had a question about my order. The product itself is top tier. Highly recommended for serious research.

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📚 Research Bibliography

Sources & References

All clinical data and research findings cited on this page are sourced from peer-
reviewed journals and official publications.

BRAIN RESEARCH

Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat...

Dolotov OV, Karpenko EA, Inozemtsev...

2006 PMID: 16996037

BMC GENOMICS

The peptide semax affects the expression of genes related to the immune and vascular systems in rat...

Medvedeva EV, Dmitrieva VG...

2014 PMID: 24661656

ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S.S. KORSAKOVA

The efficacy of semax in the treatment of patients at different stages of ischemic stroke

2018 PMID: 29798983

JOURNAL OF MOLECULAR NEUROSCIENCE

Comparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus,...

Shadrina M, Kolomin T, Agapova T, et...

2010 PMID: 19662538

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Molecular Level

2020 PMID: 32575851

ALZHEIMER'S DRUG DISCOVERY FOUNDATION

Semax - Cognitive Vitality For Researchers

PUBCHEM DATABASE

Semax - Compound Summary (CID 9811102)

PMID: 9811102

⚠️ Important Research Notice

This product is sold exclusively for in vitro research and educational purposes. It is not intended for human or veterinary use, and is not intended to diagnose, treat, cure, or prevent any medical condition or disease. All clinical trial data, research findings, and scientific information presented on this page are sourced from peer-reviewed academic publications. This content is provided for educational reference only and does not constitute medical advice, product claims, or treatment recommendations. By purchasing this product, the buyer confirms they are a qualified researcher and will use it strictly in accordance with all applicable federal, state, and local laws and regulations. GMR Peptides assumes no liability for any misuse of this product outside of a research context.

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🔬 Research Use Only

Semax Research Peptide

Select Dosage

Bundle & Save

1 bottle

Buy 2, Get 1 Free

1 bottle

Buy 2, Get 1 Free

Mix & Match: Buy 2, Get 1 Free

Bacteriostatic water Research Peptide

SSL 256-bit

Free shipping

60-day returns

We Accept

🔬 Research Use Only

Semax Research Peptide

Select Dosage

Bundle & Save

1 bottle

Buy 2, Get 1 Free

Bacteriostatic water Research Peptide

We Accept

99%+ Purity Guaranteed

Shipment Protection

60-Day Money Back

Certificate of Analysis and Peptide Purity Verification

🧪 Lab Verified

Semax - 10mg Vial

Compound Information

Semax Molecular Overview

Handling and Context

Observation Summary

What Researchers Say

Write a Review

📚 Research Bibliography

Sources & References

Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat...

The peptide semax affects the expression of genes related to the immune and vascular systems in rat...

The efficacy of semax in the treatment of patients at different stages of ischemic stroke

Comparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus,...

Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Molecular Level

Semax - Cognitive Vitality For Researchers

Semax - Compound Summary (CID 9811102)

⚠️ Important Research Notice

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THIS IS NOT FOR HUMAN CONSUMPTION